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Gi alpha subunit
Gi alpha subunit (Gαi, or Gi/G0 or Gi protein) is a heterotrimeric G protein subunit that inhibits the production of cAMP from ATP. A mnemonic for remembering this subunit is to look at first letter (Gαi = Adenylate Cyclase inhibitor). == Receptors ==
The following G protein-coupled receptors couple to the Gi subunit: * Acetylcholine M2 & M4 receptors * Adenosine A1 & A3 receptors * Adrenergic α2A, α2B, & α2C receptors * Apelin receptors * Calcium-sensing receptor * Cannabinoid receptors (CB1 and CB2) * Chemokine CXCR4 receptor * Dopamine D2, D3, D4 * GABAB receptor * Glutamate mGluR2, mGluR3, mGluR4, mGluR6, mGluR7, & mGluR8 receptors * Histamine H3 & H4 receptors * Melatonin MT1, MT2, & MT3 receptors * Niacin receptors NIACR1 & NIACR2 * Opioid δ, κ, μ, & nociceptin receptors * Prostaglandin EP1, EP3, FP, & TP receptors * Serotonin 5-HT1 & 5-HT5 receptors * Short chain fatty acid receptors: FFAR2 & FFAR3 * Somatostatin sst1, sst2, sst3, sst4 & sst5 receptors * Trace amine-associated receptor 8
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Gi alpha subunit」の詳細全文を読む
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